By Olena Harmash and Max Hunder

KYIV (Reuters) -A Russian missile hit a clinic in the eastern Ukrainian city of Dnipro on Friday, killing at least two people and wounding 23 in an attack that President Volodymyr Zelenskiy described as a crime against humanity.

Video footage showed a devastated building with smoke pouring out of it and rescue workers looking on. Much of the upper floor of what appeared to be a three-storey building had been badly damaged. A covered corpse lay in the road nearby.

"Another (Russian) missile attack, another crime against humanity," Zelenskiy wrote on Twitter, describing the damage to a psychological clinic and a veterinary clinic in Dnipro.

"Only an evil state can fight against clinics. There can be no military purpose in this. It is pure Russian terror."

Regional governor Serhiy Lysak said a 69-year-old man had been killed, adding: "He was just passing by when the Russian terrorists' rocket hit the city."

The governor said another man's body had been pulled out of the rubble, and that 21 of the 23 wounded had been taken to hospital. Three were seriously hurt, he said.

The Ukrainian Defence Ministry called it a serious war crime under the Geneva Conventions, which set out how soldiers and civilians should be treated in war.

Russia's Defence Ministry said it had carried out an overnight strike on Ukrainian ammunition depots.

"The target of the strike has been achieved. All designated facilities were hit," the RIA news agency quoted it as saying.

Moscow has dismissed allegations that its soldiers have committed war crimes and denies deliberately targeting civilians although it has bombarded cities across Ukraine since invading 15 months ago.

OVERNIGHT ATTACKS

Moscow said earlier on Friday Ukraine had struck two regions in southern Russia with a rocket and a drone, but the missile was shot down by its air defences.

Ukraine said its air defences had shot down 10 missiles and more than 20 drones launched by Russia in overnight attacks on Dnipro, the capital Kyiv and eastern regions.

Zelenskiy's office said a fire had broken out on the outskirts of the northeastern city of Kharkiv after an oil depot was hit twice, and that equipment for pumping oil products had been damaged.

After months of attacks on energy infrastructure, Russia has shifted the focus of its missile strikes to try to disrupt preparations for a Ukrainian counterattack, a senior military intelligence official said last week. Attacks were increasingly targeting military facilities and supplies, he said.

(Editing by Timothy Heritage)